Risk factors and early detection of breast cancer: facts, questions, and genome-based perspectives.

نویسنده

  • Demosthenes E Ziogas
چکیده

1. Narod SA. Early-onset breast cancer: what do we know about the risk factors? A Countercurrents Series. Curr Oncol 2011;18:204–5. 2. Green ED, Guyer MS on behalf of National Human Genome Research Institute. Charting a course for genomic medicine from base pairs to bedside. Nature 2011;470:204–13. 3. Ruder WC, Lu T, Collins JJ. Synthetic biology moving into the clinic. Science 2011;333:1248–52. 4. Ziogas DE, Roukos DH. Genome diagnostics: next-generation sequencing, new genome-wide association studies and clinical challenges. Expert Rev Mol Diagn 2011;11:663–6. 5. Katsios C, Roukos DH. Individual genomes and personalized medicine: life diversity and complexity. Per Med 2010;7:347–50. 6. Roukos DH. Personal genomics and genome-wide association studies: novel discoveries but limitations for practical personalized medicine. Ann Surg Oncol 2009;16:772–3. 7. Roukos DH. Bionetworks-based personalized medicine versus comparative-effectiveness research or harmonization of both in cancer management? Expert Rev Mol Diagn 2010;10:247–50. 8. Roukos DH. Complete genome sequencing and network modeling to overcome trastuzumab resistance. Pharmacogenomics 2010;11:1039–43. 9. Roukos DH. Next-generation, genome sequencing-based biomarkers: concerns and challenges for medical practice. Biomark Med 2010;4:583–6. The Editor Current Oncology March 28, 2012

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Molecular epidemiology of Human Papillomaviruses in breast cancer, Golestan province of Iran

Abstract Background and objectives: Breast cancer is the most prevalent one in women. Some of the common causative factors are genetic background, nutritional and environmental factors. Viruses are believed as a risk factor in this cancer, too. Recent studies reported that Human Papillomaviruses can be one of the possible risk factors of breast cancer. This study focused on investigation of the...

متن کامل

مروری بر نئوپلاسم پستان در زنان

Introduction: Breast cancer is an uncontrollable growth of abnormal cells in different areas of the chest. Research about the causes of breast cancer is crucial. Finding cancers risk factor can lead to identification of women at risk, prevention strategies, and screening for early detection of disease. In this paper, we tried to survey the risk factors that lead to the creation of this common c...

متن کامل

Male Breast Cancer; A Review of Risk Factors and Clinical and Radiological Features

While male breast cancer (MBC) consists only 1% of all breast cancers in the United States, approximately 2000 men are diagnosed annually and the incidence seems to be slowly increasing. About 50% of men have axillary nodal metastasis at the time of diagnosis. A mean delay of 6 to 10 months occurs in the diagnosis of MBC, which leads to the progression of the disease before presentation. More t...

متن کامل

Male Breast Cancer; A Review of Risk Factors and Clinical and Radiological Features

While male breast cancer (MBC) consists only 1% of all breast cancers in the United States, approximately 2000 men are diagnosed annually and the incidence seems to be slowly increasing. About 50% of men have axillary nodal metastasis at the time of diagnosis. A mean delay of 6 to 10 months occurs in the diagnosis of MBC, which leads to the progression of the disease before presentation. More t...

متن کامل

Applying Two Computational Classification Methods to Predict the Risk of Breast Cancer: A Comparative Study

Introduction: Lack of a proper method for early detection and diagnostic errors in medicine are some fundamental problems in treating cancer. Data analysis techniques may significantly help early diagnosis. The current study aimed at applying and evaluating neural networks and decision tree algorithm on breast cancer patients’ data for early cancer prediction. Methods: In the current stu...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Current oncology

دوره 19 3  شماره 

صفحات  -

تاریخ انتشار 2012